The mysteriously named P11 is a protein that interacts with seratonin.  Can it really help treat depression? And if it can, how do you get it in your head?  Meanwhile, Cathi has a rather more invasive idea...finding the deep recesses of the brain's Sector 25, the "sad centre". 

Meanwhile, Office-in-a-Bucket picks up where other inventions we've pointed to left off.  Like the paraSITE inflatable residence for homeless people, or the "Being Room" that lets you be alone...together, the Office-in-a-Bucket aims to give you a private inflatable meeting room anywhere you like.

And, who needs a whole club to have fun?  Why not rev up the Party Car?

P11 Research: http://www.ctv.ca/servlet/ArticleNews/story/CTVNews/20060105/depression_protein_060105?s_name=&no_ads=

The Sadness Centre Surgery:
http://www.cbc.ca/quirks/archives/05-06/jan21.html 

Trepaning Apparently a Real Historical Fact:
http://en.wikipedia.org/wiki/Trepanning

Don't Kick the Bucket, Inflate it!
http://www.inflate.co.uk/oiab/

Party Car
http://www.gizmag.com/go/3950/